Contents
- 1 How much weight loss in a week?
- 2 Does orlistat speed up metabolism?
- 3 Is tiredness a side effect of orlistat?
- 4 Does orlistat reduce fat absorption?
How much weight can I lose in a week with orlistat?
How much weight should I be losing? 1-2lb (0.5-1kg) per week – the same as at phase 1. The aim is to lose 5% of your body weight in the first 12 weeks. If you manage this you may be able to keep taking Xenical during phase 3.
How quickly do you see results with orlistat?
Orlistat is a prescription weight loss tablet that changes how your body absorbs fat from food. It starts working within 2 days, and you should start to see weight loss within a few weeks of taking it. Kick-start your weight loss journey with Next Day Click & Collect.
How many pounds do you lose with orlistat?
What is orlistat? – Orlistat (brand name: alli) is an FDA-approved OTC medication that can help overweight adults lose weight. Orlistat works by blocking fat from being absorbed into the body after it is eaten during a meal. Approximately 5 to 10 pounds may be lost during the first 6 months of orlistat use.
How much weight loss in a week?
3. Set realistic goals – It may seem obvious to set realistic weight-loss goals. But do you really know what’s realistic? Over the long term, it’s smart to aim for losing 1 to 2 pounds (0.5 to 1 kilogram) a week. Generally to lose 1 to 2 pounds a week, you need to burn 500 to 1,000 calories more than you consume each day, through a lower calorie diet and regular physical activity.
- Depending on your weight, 5% of your current weight may be a realistic goal, at least for an initial goal.
- If you weigh 180 pounds (82 kilograms), that’s 9 pounds (4 kilograms).
- Even this level of weight loss can help lower your risk of chronic health problems, such as heart disease and type 2 diabetes.
When you’re setting goals, think about both process and outcome goals. “Walk every day for 30 minutes” is an example of a process goal. “Lose 10 pounds” is an example of an outcome goal. It isn’t essential that you have an outcome goal, but you should set process goals because changing your habits is a key to weight loss.
Does orlistat speed up metabolism?
Conclusions – Orlistat treatment improved oxysterol metabolism in overweight and obese adults, and the favorable changes in oxysterol were maintained until 6 months after orlistat treatment ended. Thus, orlistat may have pivotal role in the process of endothelial dysfunction and atherosclerosis via oxysterol modulation.
How do I know if orlistat is working?
Uses – This is used with a doctor-approved, behavior change, and reduced-calorie diet program to help you lose, It is used by certain people, such as those who are or have -related medical problems. Taking can also help keep you from gaining back you have lost.
- And keeping it off can lessen the many health risks that come with, including,,, and a shorter life.Dietary fats need to be broken down into smaller pieces before the body can absorb them.
- Orlistat works by blocking the that breaks down fats in your diet.
- This undigested then passes out of your body in your,
Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories. If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this,
If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your before you start taking and each time you get a refill. Take this medication as directed by your doctor, by with liquid sometime during each meal that contains or within 1 hour after the meal, usually 3 times daily.
If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Because this drug can interfere with the absorption of certain (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these is recommended.
Take the multivitamin at least 2 hours before or 2 hours after taking orlistat (such as at ). If you take, take it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take, take it at least 4 hours before or after orlistat.
Will I gain weight after stopping orlistat?
Some people who take orlistat regain the weight they have lost when they stop taking it. You should make permanent, life-long changes towards a healthier lifestyle whilst taking orlistat to minimise weight regain when you stop taking the medication.
What happens if you eat fat on orlistat?
What happens if I eat too much fat while taking Xenical/Orlistat? – You don’t need to completely cut out fatty foods when you’re taking orlistat – in fact if you eat a very low fat diet, Orlistat won’t work properly. Over time you will notice where the hidden fats are: if your fat intake is high, you will get oily stools.
Does everyone lose weight on orlistat?
Orlistat has helped some people lose 10% or more of their body weight in just six months. In some cases, it is ineffective. One reason orlistat may not work is that you may believe you may relax your weight-loss diet since orlistat will take care of everything.
How fast do you lose weight after starting Xenical?
Uses – This is used with a doctor-approved, behavior change, and reduced-calorie diet program to help you lose, It is used by certain people, such as those who are or have -related medical problems. Taking can also help keep you from gaining back you have lost.
and keeping it off can lessen the many health risks that come with, including,,, and a shorter life.Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the that breaks down fats in your diet. This undigested then passes out of your body in your,
Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories. If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this,
- If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your before you start taking and each time you get a refill.
- Take this medication as directed by your doctor, by with liquid sometime during each meal that contains or within 1 hour after the meal, usually 3 times daily.
If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Because this drug can interfere with the absorption of certain (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these is recommended.
Take the multivitamin at least 2 hours before or 2 hours after taking orlistat (such as at ). If you take, take it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take, take it at least 4 hours before or after orlistat.
Can you lose 2kg a week?
It is possible to lose weight quickly and safely, and keep it off. You know the best bit? You don’t even have to hit the gym. When you consider that a sack of potatoes weighs in at 2kg, imagine how amazing it would feel to be 2kg lighter this time next week.
Can I lose 5kg in a week?
How Do I Lose 5 Kilos A Week Through Calorie Deficit? – Whether it’s for a special event or just to kickstart a weight loss journey, the desire to shed a few extra pounds quickly can be tempting. However, the question remains: how do I lose 5 kilos in just a week? Here Is The Answer You Are Looking For: So, if you want to lose 5 kg (which is equivalent to 11 pounds) in one week, you would need to create a calorie deficit of 38,500 calories over that week.
- This means that you would need to burn or cut 5,500 calories per day in order to achieve this level of weight loss.
- To put this in perspective, a moderately active adult male needs around 2500-3000 calories per day.
- To maintain their weight, a moderately active adult female needs around 2000-2500 calories per day.
So, in order to create a calorie deficit of 5,500 calories per day, You would need to consume only 500-1,000 calories per day, which is an extremely low amount and likely not sustainable or healthy for most people. In fact, trying to lose 5 kg in one week is generally not realistic or healthy.
Rapid weight loss can lead to muscle loss, nutrient deficiencies, and other negative health effects. Additionally, most of the weight lost during rapid weight loss is often water weight or muscle mass rather than body fat. Sustainable weight loss should be achieved at a rate of 0.5-1 kg per week through a combination of healthy eating habits and regular physical activity.
While it may be tempting to try to reduce 5 kgs in a week, it is not a realistic or healthy goal for most people. Instead, it’s important to focus on making sustainable lifestyle changes that will lead to gradual and long-term weight loss.
How much weight can you lose in 3 months with orlistat?
How long does it take to work? It works straight away with every meal. But this isn’t a crash diet – we expect you to lose around 5% of your starting body weight, every 3 months. This means if you currently weigh 90kg, we’d expect you to lose 4.5kg in 3 months.
Is tiredness a side effect of orlistat?
Precautions – It is very important that your doctor check your or your child’s progress at regular visits, to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. Using this medicine while you are pregnant can harm your unborn baby.
- Use an effective form of birth control to keep from getting pregnant.
- If you think you have become pregnant while using this medicine, tell your doctor right away.
- For patients with diabetes: Weight loss may result in an improvement in your condition, and your doctor may need to change your dose of oral diabetes medicine or insulin.
This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using this medicine.
Stop using this medicine and check with your doctor right away if you or your child have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual itching; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.
This medicine may increase your risk of having kidney stones. Check with your doctor right away if you or your child have blood in the urine, nausea and vomiting, pain in the groin or genitals, or sharp back pain just below the ribs. Weight loss with this medicine may increase your risk of having gallstones.
Does orlistat reduce fat absorption?
Mechanism of Action – Orlistat acts by reversibly inhibiting gastric and pancreatic lipases. These lipases have an important role in the digestion of dietary fat. They work by breaking down the triglycerides into absorbable free fatty acids and monoglycerides.
Orlistat covalently binds to the serine residues of active sites of lipases and inactivates them. The inactivation of lipases prevents the hydrolysis of triglycerides, and thus free fatty acids are not absorbed. The primary action of orlistat is local lipase inhibition within the gut. Systemic absorption is not necessary for the activity of orlistat.
At the recommended dosage, orlistat inhibits dietary fat absorption (approximately 30%). According to AHA, the percentage change in weight is also associated with a small reduction in blood pressure. Research also suggested that orlistat has a beneficial consequence on carbohydrate metabolism.
Absorption: Orlistat acts mainly via its local effect in the gut, and systemic exposure to the medication is minimal. Distribution: Most (more than 99%) of the drug is bound to the plasma proteins (lipoproteins and albumin are the major binding proteins). Metabolism: Orlistat metabolism is primarily within the intestinal wall. Elimination: 95 to 97% of the medication is unabsorbed and excreted in feces.
How many calories should you eat on orlistat?
Lunch ideas – If your goal is 1,500 calories a day, aim for roughly 400 calories at breakfast, lunch and dinner, with two snacks of about 150 calories each. You’ll get more nutritional bang out of your calories if you choose whole foods like vegetables, fruit, beans, nuts and seeds. Here are some delicious and nutritious lunch recipes to attempt:
Stuffed Ranchero Sweet Potato – This recipe is perfect to pack up when you’re on the go! One sweet potato provides over 300% of your daily vitamin A needs and comes packed with other sassy nutrients. Edamame & Veggie Rice Bowl – This vegan grain bowl is easy to make ahead of time to enjoy hot or cold for lunch the next day. With a punchy citrus dressing offsetting the sweetness of the roasted vegetables, you’ll get a deep, satisfying flavour that keeps you going for hours. Spiralized Asian Quinoa Salad with Peanut Dressing – Noodles, anyone? Get in your veggies with this Asian Quinoa Salad. It soaks up the flavour of the peanut dressing as it sits, so it’s perfect for making at the beginning of the week and having for lunch for days! Baked Cod With a Tangy Topping – Perfect for pepping up your afternoon, this fish dish packs a powerful punch – and it’s super easy to make. Carrot & Coriander Soup – Soup is the ideal diet comfort food: filling, low-calorie, and delicious. This vegetarian recipe is exceptionally healthy and can be prepared in no time. Sesame Chicken Stir-Fry – Dietary restrictions don’t mean giving up strong flavours. This mouth-watering chicken dish is sure to satisfy your lunchtime cravings.
Can you eat chocolate on Xenical?
To gain optimal benefit, avoid the intake of food containing fat between meals, such as biscuits, chocolate and savoury snacks. Xenical only works in the presence of dietary fat. Therefore, if you miss a main meal or if you have a meal containing no fat, Xenical need not be taken.
Does orlistat work on visceral fat?
Safety and Tolerability – The incidence of adverse reactions is shown in Table, There were 142 adverse reactions observed in 73 of the 120 participants (60.8%). Of these, 133 were episodes of defecation-related symptoms such as oily spotting and flatus with discharge due to the pharmacologic effects of the lipase inhibitor, observed in 70 participants (58.3%). Additionally, there were two incidences of hepatic function abnormal in two participants (1.7%), two incidences of hyperuricemia in one participant (0.8%), and a single incidence of hyperbilirubinemia, dysuria, cough, skin erosion, and liver function test abnormal in one participant (0.8%). The severity of these adverse reactions was categorized as follows: 140 mild episodes in 73 participants (60.8%) and two moderate episodes in one participant (0.8%). No serious or severe adverse reactions were observed. Only two adverse reactions required medical treatment (gastritis and skin erosion), which resolved with pharmacologic intervention. There were no remarkable differences in the frequency of adverse reactions with respect to participant baseline characteristics (age, gender, BMI, etc.). Table 4 Incidence of adverse reactions The incidence of adverse reactions by time is shown in Fig., Of the 142 adverse reactions that occurred during the treatment term, 92 (64.8%) occurred during the first 4 weeks (0–35 days) of the treatment term. Subsequently, there were one (0.7%) to 10 (7.0%) adverse reactions per assessment interval (Fig. a). Similar results were observed for defecation-related symptoms, with 90 of the 133 adverse reaction episodes (67.7%) occurring in the first 4 weeks of the treatment term and subsequently one (0.8%) to 10 (7.5%) adverse reactions per assessment interval (Fig. b). Fig.6 Incidence of adverse reactions by time. Percentages are calculated as the number of adverse reactions per assessment interval over the total number of adverse reactions during the entire treatment term. a Incidence of all adverse reactions; b incidence of defecation-related adverse reactions. In both a and b, the majority of adverse reactions occurred within the first 4 weeks (0–35 days) of treatment; frequency of adverse reactions did not increase with longer administration time As mentioned above, defecation-related symptoms were the most common adverse reactions. Specifically, those symptoms that occurred in ≥ 5% of participants included oily spotting, flatus with discharge, fatty/oily stool, fecal incontinence, and liquid stool, These symptoms were mostly mild, reversible, and recognizable by the participants; none were serious or severe. No participants were advised by the physician to withdraw from treatment. No adverse reactions related to fat-soluble vitamin deficiencies were observed, and no participants required treatment or vitamin supplementation. Changes in vitamin A (retinol), vitamin D (25-OH vitamin D), and vitamin E (tocopherol) during the treatment term are shown in Fig., Significant differences were observed, with a change from baseline to week 52 of the treatment term of 34.8 ± 87.1 ng/ml (mean ± SD) for vitamin A, 2.36 ± 5.11 ng/ml for vitamin D, and − 0.081 ± 0.197 mg/dl for vitamin E ( p < 0.001 for all parameters). Notably, only vitamin E showed a reduction. Although vitamin E levels at whole term after week 4 were lower than those at baseline, the levels did not continue to reduce. Further, the observed changes were within the normal ranges, and no other remarkable changes were observed. All other laboratory tests showed changes within their normal ranges, with no notable changes or safety concerns. Fig.7 Changes in fat-soluble vitamin concentrations. Mean ± SD. n (week 52): a 114, b 114, c 114. *Paired Wilcoxon test, p < 0.05 compared with baseline. a Vitamin A (retinol); b vitamin D (25-OH vitamin D); c vitamin E (tocopherol). Although all parameters showed significant differences compared with baseline at a certain term, all changes were within their normal ranges. No notable changes in terms of safety were observed. SD standard deviation This study was the first to evaluate the efficacy and safety of 52-week administration of orlistat (60 mg, administered three times daily) in Japanese participants with excessive visceral fat accumulation and without metabolic diseases. In terms of efficacy, 52-week administration of orlistat 60 mg reduced the visceral fat area in Japanese participants with excessive visceral fat accumulation and without metabolic diseases; these effects continued after 24 weeks, which is a new finding. At week 52 of the treatment term, the change from baseline in visceral fat area was − 21.52% ± 1.89% (mean ± SE). The visceral fat area reduced during the 12-week observation term as a result of improvement in diet and maintenance of exercise habits, and it continued to reduce gradually throughout the entire 52-week treatment term without returning to baseline levels. Significant reductions in visceral fat area were observed at whole term compared with baseline. Additionally, the subcutaneous fat area reduced, and waist circumference, which consists of visceral fat and subcutaneous fat, also decreased. These results suggest that the use of orlistat reduces the risk of developing metabolic diseases resulting from excessive visceral fat accumulation by enhancing the effects of lifestyle improvement in Japanese participants with excessive visceral fat accumulation and without metabolic diseases. Orlistat, therefore, may be a useful option for early intervention in obesity. Moreover, based on orlistat's mechanism of action, it is conceivable that the suppression of dietary fat absorption enhances the utilization of lipids in the body, which may further lead to reductions in visceral fat and body weight. Reduction in waist circumference can be attributed to subsequent abdominal fat reduction. In Europe and the US, a 60-mg formulation of orlistat for administration three times daily is available without a prescription. Multiple reports have confirmed the safety and efficacy of orlistat in individuals with severe obesity in these countries, and significant body weight changes were observed as well in a previous study (orlistat was administered three times daily for 104 weeks at a dose of 60 mg to severely obese patients with BMIs between 30 and 44 kg/m 2 ). Central appetite suppressants, such as lorcaserin and the combination of bupropion and naltrexone, are used as anti-obesity drugs in Europe and the USA. Significant body weight reductions have been demonstrated in clinical studies for lorcaserin (in obese patients with BMI 30–45 kg/m 2 or those with BMI ≥ 27 kg/m 2 with hypertension and/or dyslipidemia) and the combination of bupropion and naltrexone (in obese patients with BMI ≥ 30 kg/m 2 or those with BMI ≥ 27 kg/m 2 with hypertension and/or dyslipidemia), Furthermore, the frequency of headache, nausea, and dizziness was higher in the lorcaserin group compared with placebo; the combination of bupropion and naltrexone caused nausea, headache, constipation, dizziness, and dry mouth, However, because orlistat has very little absorption in the body, these symptoms were not observed in individuals taking orlistat (with the exception of constipation). Waist circumference was used to select participants for this study, and, as a result, participants with a visceral fat area < 100 cm 2 were included in this study (19.2%) (as in another study ). Notably, not only was the visceral fat area reduced in these participants, but waist circumference, which serves as a surrogate index for visceral fat, was also reduced. Orlistat inhibits the absorption of dietary fat by 25%–30% and is therefore presumed to reduce the concentration of lipids in the blood. In this study, all lipid parameters (total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides) showed significant differences compared with baseline at some terms. However, only total cholesterol and LDL cholesterol levels showed a reducing trend throughout the 52-week treatment term with significant reductions from baseline at whole term. In a meta-analysis by Tian Hu et al., participants receiving a low-carbohydrate diet showed a greater increase in HDL cholesterol and a reduction in triglycerides compared with those receiving a low-fat diet, but experienced less reduction in total cholesterol and LDL cholesterol compared with those receiving a low-fat diet, Orlistat, then, likely did not affect HDL cholesterol or triglycerides, which are more likely to be affected by carbohydrate intake than fat intake, as orlistat's mechanism of action inhibits the absorption of food-derived fat. It is well established that body weight loss inhibits the progression of metabolic diseases resulting from insulin resistance in individuals with obesity, In this study, the effects of orlistat on blood glucose levels and blood pressure were not clear, partly because most of the participants had both normal blood glucose and normal blood pressure at baseline. However, it may be reasonable to expect that orlistat prevents the aggravation of blood glucose and blood pressure imbalances in the long term. Moreover, in this study, 26 of the 64 participants with one or more risk factors at baseline (40.6%) had no risk factors at week 52 of treatment, and all seven participants who had two or more risk factors at baseline had fewer risk factors at week 52. By demonstrating reductions in total cholesterol, LDL cholesterol, visceral fat area, waist circumference, and the number of metabolic disease risk factors, the clinical significance of orlistat as a potential benefit for Japanese participants with excessive visceral fat accumulation and without metabolic diseases was confirmed. Furthermore, a study suggesting high blood pressure, high blood glucose, and abnormal lipid metabolism to be cardiovascular risk factors showed reductions in the number of metabolic disease risk factors as well as visceral fat area with the use of orlistat, which may ultimately lead to a reduced risk of cardiovascular diseases. In terms of safety, 142 adverse reactions in 73 of the 120 participants (60.8%) were observed. However, most of these were defecation-related symptoms such as oily spotting and flatus with discharge due to the pharmacologic effects of the lipase inhibitor. The majority of these symptoms were mild, reversible, and recognizable by the participant; none were serious or severe. Few adverse reactions required medical treatment, and no participants were advised by the investigator to withdraw from treatment. The frequency of adverse reactions observed in this study does not exceed that observed in previous studies of orlistat 60 mg conducted in other countries as an over-the-counter drug (including defecation-related adverse reactions) ; therefore, it is reasonable to assume that orlistat is also sufficiently tolerable with self-management in the Japanese population. Moreover, among the 133 defecation-related adverse reactions that occurred during the treatment term, the majority (90 episodes, 67.7%) occurred during the first 4 weeks of the treatment term, and most of these participants were able to continue the 52-week term (a few participants withdrew from the study at their request). Because orlistat inhibits the absorption of dietary fat by inactivating lipase, a lipolytic enzyme, the absorption of fat-soluble vitamins such as A, D, and E could also be inhibited. No adverse reactions related to fat-soluble vitamin deficiencies were observed, and no participants required treatment or vitamin supplementation. In this study, levels of vitamin A and vitamin D at week 52 were higher than those at baseline; levels of vitamin E, however, decreased by − 0.081 ± 0.197 mg/dl (mean ± SD). Although there was a statistically significant reduction in vitamin E at week 52 of the treatment term, levels did not subsequently continue to reduce. Therefore, it is doubtful that this change is clinically meaningful. Further, the observed changes in this study were within the normal ranges, and no other remarkable changes were observed. All other laboratory tests showed changes within their normal ranges, and no notable changes were observed with regard to safety. Throughout the treatment term of this study, > 90% of participants had a compliance rate of 100% for dietary improvement. Among the remaining participants, none had a compliance rate < 80%. Therefore, orlistat can also be a useful option when used as a complement to diet and maintenance of exercise habits in the long term. The open-label design and lack of a control group are limitations of this study and may have contributed to observational bias of the investigators and high expectations of participants. In this study, we selected participants and measured the efficacy based on waist circumference. Thus, it is conceivable that users of orlistat can monitor feasibility of drug use and its effects by using their waist circumference as an indicator. Considering the fact that orlistat 60 mg is already available as an over-the-counter drug in several countries, for Japanese participants with excessive visceral fat accumulation and without metabolic diseases, orlistat is expected to provide significant potential benefits. It was confirmed that the 52-week administration of orlistat 60 mg three times daily was effective in reducing the visceral fat area and waist circumference and was sufficiently tolerated by Japanese participants with excessive visceral fat accumulation and without metabolic diseases when their diet was improved and exercise habits were maintained. The longer orlistat is administered, the more visceral fat is expected to decrease; moreover, it may lead to reductions in risk factors for metabolic diseases caused by obesity.
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The authors would like to thank the participants, investigators, and other staff members for their invaluable contributions to the study. We would like to thank Dr. Ichiro Tatsuno (Sakura Medical Center, Toho University) and Dr. Yutaka Kimura (Kansai Medical University) for support and implementation of this study.
What happens if I eat too much fat on orlistat?
It is recommended that you choose low fat foods more often, as eating foods higher in fat causes side effects which can be unpleasant. Some side effects include wind, diarrhoea, smelly stools, being unable to control the movement of your bowels and an urgency to pass stools.
How to lose the most weight with orlistat?
When taking Orlistat, it’s important to eat a healthy, balanced diet to get the best results. You’ll also need to eat a low fat diet, so you should aim to get no more than 30% of your daily calories from fat.
How fast do you lose weight after starting Xenical?
Uses – This is used with a doctor-approved, behavior change, and reduced-calorie diet program to help you lose, It is used by certain people, such as those who are or have -related medical problems. Taking can also help keep you from gaining back you have lost.
and keeping it off can lessen the many health risks that come with, including,,, and a shorter life.Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the that breaks down fats in your diet. This undigested then passes out of your body in your,
Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories. If you are taking the over-the-counter product to self-treat, read all directions on the product package before taking this,
- If your doctor has prescribed this medication, read the Patient Information Leaflet if available from your before you start taking and each time you get a refill.
- Take this medication as directed by your doctor, by with liquid sometime during each meal that contains or within 1 hour after the meal, usually 3 times daily.
If you miss a meal or your meal contains no fat, skip that dose of the medication. To decrease the chance of unpleasant side effects, it is very important that no more than 30% of the calories in your diet come from fat. Your daily intake of fat, protein, and carbohydrates should be evenly spread over 3 main meals.
- Do not increase your dose or use this drug more often or for longer than prescribed.
- Your condition will not improve any faster, and your risk of side effects will increase.
- Because this drug can interfere with the absorption of certain (fat-soluble vitamins including A, D, E, K), a daily multivitamin supplement containing these is recommended.
Take the multivitamin at least 2 hours before or 2 hours after taking orlistat (such as at ). If you take, take it at least 3 hours before or after orlistat to make sure the full dose of cyclosporine is absorbed into your bloodstream. If you take, take it at least 4 hours before or after orlistat.
Can I take 4 Xenical a day?
Recommended Dosing – The recommended dose of XENICAL is one 120-mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal). The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat.
- The daily intake of fat, carbohydrate, and protein should be distributed over three main meals.
- If a meal is occasionally missed or contains no fat, the dose of XENICAL can be omitted.
- Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene, patients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition,
The vitamin supplement should be taken at least 2 hours before or after the administration of XENICAL, such as at bedtime. For patients receiving both XENICAL and cyclosporine therapy, administer cyclosporine 3 hours after XENICAL. For patients receiving both XENICAL and levothyroxine therapy, administer levothyroxine and XENICAL at least 4 hours apart.
Patients treated concomitantly with XENICAL and levothyroxine should be monitored for changes in thyroid function. Doses above 120 mg three times a day have not been shown to provide additional benefit. Based on fecal fat measurements, the effect of XENICAL is seen as soon as 24 to 48 hours after dosing.
Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours.